AROMATIC BORON-CONTAINING COMPOUNDS AND INSULIN ANALOGS

The present disclosure relates to novel compounds that include one or more aromatic boron-containing groups. The present disclosure further relates to pharmaceutical compositions containing such compounds, and their use in prevention and treatment of disorders, such as hyperglycemia, type 2 diabetes...

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Main Authors SHAKER Mirna Ekram Anwar, MALI Sachitanand, STEELE Jack Joseph, SPENCER Ryan Kelly, LIANG Jingxin, CHEN Diao, MAHDAVI Alborz
Format Patent
LanguageEnglish
Spanish
Published 29.05.2023
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Summary:The present disclosure relates to novel compounds that include one or more aromatic boron-containing groups. The present disclosure further relates to pharmaceutical compositions containing such compounds, and their use in prevention and treatment of disorders, such as hyperglycemia, type 2 diabetes, impaired glucose tolerance, type 1 diabetes, obesity, metabolic syndrome X, or dyslipidemia, diabetes during pregnancy, pre-diabetes, Alzheimer's disease, MODY 1, MODY 2 or MODY 3 diabetes, mood disorders, and psychiatric disorders. La presente divulgación se refiere a nuevos compuestos que incluyen uno o más grupos aromáticos que contienen boro. La presente divulgación se refiere además a composiciones farmacéuticas que contienen tales compuestos, y su uso en la prevención y el tratamiento de trastornos, tales como hiperglucemia, diabetes tipo 2, intolerancia a la glucosa, diabetes tipo 1, obesidad, síndrome metabólico X o dislipidemia, diabetes durante el embarazo, prediabetes, enfermedad de Alzheimer, diabetes MODY 1, MODY 2 o MODY 3, trastornos del estado de ánimo y trastornos psiquiátricos.
Bibliography:Application Number: MX20230005935