INHIBITORS OF THE MENIN-MLL INTERACTION

The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction. La presente invención se refiere a inhibid...

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Bibliographic Details
Main Authors HOUSTON Travis L, YUAN Jing, LOTESTA Stephen D, ZHENG Yajun, DILLARD Lawrence Wayne, CACATIAN Salvacion, MARCUS Andrew, MORALES-RAMOS Angel, PARENT Stephan D, SINGH Suresh B, CLAREMON David A, VENKATRAMAN Shankar, JIA Lanqui, ZHUANG Linghang, DONG Chengguo, FAN Yi
Format Patent
LanguageEnglish
Spanish
Published 10.04.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction. La presente invención se refiere a inhibidores de la interacción de menina con MLL y proteínas de fusión de MLL, composiciones farmacéuticas que contienen los mismos, y su uso en el tratamiento de cáncer y otras enfermedades mediadas por la interacción de menina-MLL.
Bibliography:Application Number: MX20230002982