ANTAGONIST COMPOUNDS

The present invention relates to compounds of formula (I) shown below: wherein R1, R2, R3, R4, R5 and R6 are each as defined in the application. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in...

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Bibliographic Details
Main Authors MCMAHON Pearl Siobhan, MOULTON Ben, WALKER Edward Richard, MCCARTHY Clive
Format Patent
LanguageEnglish
Spanish
Published 20.04.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of formula (I) shown below: wherein R1, R2, R3, R4, R5 and R6 are each as defined in the application. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or conditions in which adenosine A2a and/or A2b receptor activity is implicated, such as, for example, cancer. La presente invención se refiere a compuestos de fórmula I mostrada a continuación: (ver fórmula) en donde R1, R2, R3, R4, R5 y R6 son cada uno como se define en la solicitud. La presente invención también se refiere a procesos para preparar estos compuestos, a composiciones farmacéuticas que los comprenden y su uso en el tratamiento de enfermedades o afecciones en las que la actividad del receptor de adenosina A2a y/o A2b está involucrada, tal como, por ejemplo, el cáncer.
Bibliography:Application Number: MX20230001324