METHODS OF MAKING INCRETIN ANALOGS

Intermediate compounds are disclosed for making incretin analogs, or pharmaceutically acceptable salts thereof. In addition, methods are disclosed for making incretin analogs by coupling from two to four of the intermediate compounds herein via hybrid liquid solid phase synthesis or native chemical...

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Bibliographic Details
Main Authors LU Yu, JAMES Jinju, KOPACH Michael E, JALAN Ankur, KOBIERSKI Michael E, WHITE Timothy Donald, TSUKANOV Sergey Vladimirovich
Format Patent
LanguageEnglish
Spanish
Published 17.03.2022
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Intermediate compounds are disclosed for making incretin analogs, or pharmaceutically acceptable salts thereof. In addition, methods are disclosed for making incretin analogs by coupling from two to four of the intermediate compounds herein via hybrid liquid solid phase synthesis or native chemical ligation. Se describen compuestos intermediarios para preparar análogos de incretina o sales farmacéuticamente aceptables de estos. Además, se describen métodos para preparar análogos de incretina mediante el acoplamiento de dos a cuatro de los compuestos intermediarios de la presente descripción mediante síntesis en fase híbrida sólida líquida o unión química nativa.
Bibliography:Application Number: MX20220002115