RECOMBINANT RHABDOVIRUS ENCODING FOR CCL21

The present invention relates to the field of oncolytic viruses and in particular to a recombinant rhabdovirus, such as vesicular stomatitis virus encoding in its genome for a CCL21 protein. The invention is further directed to the use of the recombinant virus in the treatment of cancer, and also to...

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Bibliographic Details
Main Authors ERLMANN Patrik, ERB Klaus, MUELLER Philipp, WOLLMANN Guido, NOLDEN Tobias, PARK John Edward
Format Patent
LanguageEnglish
Spanish
Published 24.08.2021
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to the field of oncolytic viruses and in particular to a recombinant rhabdovirus, such as vesicular stomatitis virus encoding in its genome for a CCL21 protein. The invention is further directed to the use of the recombinant virus in the treatment of cancer, and also to methods for producing such viruses. La presente invención se refiere al campo de virus oncolíticos y, en particular, a un rhabdovirus recombinante, tal como un virus de estomatitis vesicular que codifica en su genoma una proteína CCL21. La invención también está dirigida al uso del virus recombinante en el tratamiento del cáncer, y también a métodos para producir tal virus.
Bibliography:Application Number: MX2021008927