IMMUNOGENIC COMPOSITION COMPRISING STAPHYLOCOCCAL ANTIGENS

The invention provides an immunogenic composition comprising staphylococcal antigens, containing protein antigens and conjugates of capsular polysaccharides, n particular Hla, ClfA, SpA and conjugates of capsular polysaccharides. Adjuvanted formulations are also provided. The invention may find use...

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Bibliographic Details
Main Authors GORAJ Carine, BAGNOLI Fabio
Format Patent
LanguageEnglish
Spanish
Published 25.03.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides an immunogenic composition comprising staphylococcal antigens, containing protein antigens and conjugates of capsular polysaccharides, n particular Hla, ClfA, SpA and conjugates of capsular polysaccharides. Adjuvanted formulations are also provided. The invention may find use in the prevention and treatment of staphylococcal infections, in particular S. aureus infection and disease. La invención proporciona una composición inmunogénica que comprende antígenos estafilocócicos, que contiene antígenos proteicos y conjugados de polisacáridos capsulares, en particular Hla, ClfA, SpA y conjugados de polisacáridos capsulares. También se proporcionan formulaciones adyuvantes. La invención puede encontrar uso en la prevención y el tratamiento de infecciones estafilocócicas, en particular infección y enfermedad por S. aureus.
Bibliography:Application Number: MX20200008454