APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein. Compuestos que inhiben la actividad de proteínas anti-apoptóticas Bcl-2, composiciones q...

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Main Authors Gary T. WANG, Le WANG, Aaron R. KUNZER, Xilu WANG, Gerard SULLIVAN, Robert MANTEI, Hong DING, Todd M. HANSEN, Zhi - Fu TAO, Lisa HASVOLD, Laura HEXAMER, Xiaohong SONG, Michael WENDT, Milan BRUNCKO, Andrew J. SOUERS, George DOHERTY, Steven ELMORE
Format Patent
LanguageEnglish
Spanish
Published 21.11.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein. Compuestos que inhiben la actividad de proteínas anti-apoptóticas Bcl-2, composiciones que contienen a dichos compuestos y métodos de tratamiento de enfermedades durante cuyo transcurso hay expresión de la proteína anti-apoptótica Bcl-2.
Bibliography:Application Number: MX20190012154