ENGINEERED TRAIL FOR CANCER THERAPY
Engineered single chain trail molecules are provided, as are particular mutations and combinations of mutations that improve the stability and manufacturability of such molecules. These molecules are provided for use as anti-cancer therapeutics. La presente invención se refiere a moléculas TRAIL de...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English Spanish |
| Published |
10.01.2019
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Engineered single chain trail molecules are provided, as are particular mutations and combinations of mutations that improve the stability and manufacturability of such molecules. These molecules are provided for use as anti-cancer therapeutics.
La presente invención se refiere a moléculas TRAIL de cadena sencilla diseñadas por ingeniería genética, como son mutaciones y combinaciones de mutaciones particulares que mejoran la estabilidad y manufacturabilidad de tales moléculas. Estas moléculas se proporcionan para uso como terapéuticos anti-cancerígenos. |
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| AbstractList | Engineered single chain trail molecules are provided, as are particular mutations and combinations of mutations that improve the stability and manufacturability of such molecules. These molecules are provided for use as anti-cancer therapeutics.
La presente invención se refiere a moléculas TRAIL de cadena sencilla diseñadas por ingeniería genética, como son mutaciones y combinaciones de mutaciones particulares que mejoran la estabilidad y manufacturabilidad de tales moléculas. Estas moléculas se proporcionan para uso como terapéuticos anti-cancerígenos. |
| Author | Birgit M. SCHOEBERL Diana Hung-yi Chai MARCANTONIO Eric M. TAM Stephen L. SAZINSKY |
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| DocumentTitleAlternate | TRAIL DISEÑADO POR INGENIERIA PARA TERAPIA DE CANCER. |
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| RelatedCompanies | MERRIMACK PHARMACEUTICALS, INC |
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| Snippet | Engineered single chain trail molecules are provided, as are particular mutations and combinations of mutations that improve the stability and... |
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| Title | ENGINEERED TRAIL FOR CANCER THERAPY |
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