CARBAPENEM COMPOUNDS

• Main Authors: Sheo SINGH, Shuzhi DONG, Maneesh PAUL-SATYASEELA, Sridhar Ramanathan IYER, Michael Wayne MILLER, Venkatesan PARAMESWARAN, Gopalan BALASUBRAMANIAN, Hongwu WANG, Bharani THIRUNAVUKKARASU, Prabhakar Rao GUNTURU, Venkateshwarlu JAKKALA, Chidambaram Venkateswaran SRINIVASAN, Ravi NARGUND, Katherine YOUNG, Manjula Devi DESHKUMAR, Hariharan PERIASAMY
• Format: Patent
• Language: English; Spanish
• Published: 10.01.2019
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

This invention relates to carbapenem compounds, their stereoisomers, pharmaceutically acceptable salts or N-oxides thereof, which may be useful for the treatment of bacterial infections, particularly drug-resistant bacterial infections, as well as the processes for the preparation of compounds, the pharmaceutical compositions of these compounds and their use in the treatment of bacterial infection. Esta invención se refiere a compuestos de carbapenem, sus estereoisómeros, sales farmacéuticamente aceptables o N-óxidos del mismo, que pueden ser útiles para el tratamiento de infecciones bacterianas, particularmente infecciones bacterianas resistentes a los fármacos, así como a los procesos para la preparación de compuestos, las composiciones farmacêuticas de esos compuestos y su uso en el tratamiento de infecciones bacterianas.