HYDROCHLORIDE SALT FORM FOR EZH2 INHIBITION

Provided herein are novel solid forms of N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5 -(ethyl (tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl) -[1,1'-biphenyl]-3-carboxamide hydrochloride, and related compositions and methods. Se proporcionan en la presente memor...

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Bibliographic Details
Main Authors Kevin W. KUNTZ, Steven MATHIEU, Kristen SANDERS, Hyeong-wook CHOI, Arani CHANDA
Format Patent
LanguageEnglish
Spanish
Published 28.02.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are novel solid forms of N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5 -(ethyl (tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl) -[1,1'-biphenyl]-3-carboxamide hydrochloride, and related compositions and methods. Se proporcionan en la presente memoria nuevas formas sólidas de hidrocloruro de N- ((4,6-dimetil-2-oxo1,2-dihidropiridin-3-il)meti l)-5-(etil (tetrahidro-2H-piran-4-il) amino)-4-metil-4´-(morfolino metil)-[1,1´-bifenil]-3-carboxamida y composiciones y métodos relacionados.
Bibliography:Application Number: MX20160004703