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The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compo...

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Main Authors DOMINOWSKI, PAUL JOSEPH, JULIE LYDIA FITZPATRICK, RAI, SHARATH K, MICHAEL CHRISTOPHER FONTAINE, FOSS, DENNIS L, LAUREN WILMES, KAORI MOHR, GUILLERMO GALLO, JOHN MORGAN HARDHAM, MWANGI, DUNCAN, KREBS, RICHARD LEE, SANDRA ANN MARIE LIGHTLE, SHAUNAK VORA, DAVID GEORGE EMSLIE SMITH, MEDIRATTA, SANGITA, SARAH A. SALMON, ANITA DOROTA JAGLARZ, WILLIAM DONACHIE, SUMAN MAHAN
Format Patent
LanguageEnglish
Spanish
Published 24.06.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compositions and vaccines, and use thereof in the treatment of animals. La presente invención proporciona diversas formulaciones que comprenden combinaciones de oligonucleótidos inmunoestimulantes, vehículos policatiónicos, esteroles, saponinas, aminas cuaternarias, agonistas de TLR-3, glicolípidos y MPL-A o análogos del mismo en emulsiones en aceite, el uso de las mismas en preparaciones de composiciones inmunogénicas y vacunas y el uso de las mismas en el tratamiento de animales.
Bibliography:Application Number: MX20160003658