6 - ALKYNYL PYRIDINES AS SMAC MIMETICS
This invention relates to 6-alkynyl-pyridines of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated condit...
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Main Authors | , , , , |
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Format | Patent |
Language | English Spanish |
Published |
12.11.2014
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Subjects | |
Online Access | Get full text |
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Summary: | This invention relates to 6-alkynyl-pyridines of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The groups R1 to R5 have the meanings given in the claims and in the specification.
Esta invención se refiere a 5-alquinil-piridinas de fórmula general (I) (ver Fórmula) su uso como miméticos SMAC, composiciones farmacéuticas que las contienen y su uso como medicamentos para el tratamiento y/o prevención de enfermedades caracterizadas por ecesiva o anormal proliferación celular y condiciones asociadas tal como cáncer. Los grupos R1 a R5 tienen los significados proporcionados en las reivindicaciones y en la especificación. |
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Bibliography: | Application Number: MX20140010249 |