USE OF PROPYLPARABEN AS NEUROPROTECTIVE AGENT TO ATTENUATE BRAIN DAMAGE PRODUCED BY STATUS EPILEPTICUS

The present invention describes the use of propylparaben, a widely known antimicrobial, for decreasing neuronal injury induced by Status epilepticus. An objective of the invention is the administration of propylparaben immediately after the occurrence of Status epilepticus to prevent neuronal injury...

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Main Authors CÉSAR EMMANUEL SANTANA GÓMEZ, LUIS BRUNO BLANCH, LUISA LILIA ROCHA ARRIETA, SANDRA ADELA OROZCO SUÁREZ, CAROLINA LETICIA BELLERA, ALAN TALEVI
Format Patent
LanguageEnglish
Spanish
Published 10.04.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention describes the use of propylparaben, a widely known antimicrobial, for decreasing neuronal injury induced by Status epilepticus. An objective of the invention is the administration of propylparaben immediately after the occurrence of Status epilepticus to prevent neuronal injury and the possible development of epileptogenesis, as well the neurocognitive disorders associated with this condition. La presente invención describe el uso de propilparabeno, un antimicrobiano ampliamente utilizado, para la disminución del daño neuronal inducido por Status epilepticus. Uno de los objetivos de la presente invención es la aplicación del propilparabeno inmediatamente después del Status epilepticus para evitar el daño neuronal que causa y el posible desarrollo de epileptogénesis, así como las alteraciones neurocognitivas asociadas a este padecimiento.
Bibliography:Application Number: MX20130011437