AGONISTS OF GPR40

• Main Authors: BOMMEGOWDA, Y. KENCHEGOWDA, ARUL, GEORGE FERNANDA, ARUMUGAM, NAGARAJAN, KOTTAMALAI, RAMAMOORTHY, PACHIYAPPAN, SHANMUGAM, ANGUPILLAI, SATHESH KUMAR, GEORGE, JENSON, ANSARI, MOHD MUDABBIR, RANGANATH RAO, JAGANNATH MADANAHALLI, JIDUGU, PRADEEP, RAMALINGAM, MANIVANNAN, GUDLA, CHANDRASEKHAR, RAO, D, SHIVANAGESHWARA
• Format: Patent
• Language: English; Spanish
• Published: 28.10.2013
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to compounds that have the ability to modulate the activity of GPR40 and are therefore useful in the treatment of GPR40 related disorders. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders related to GPR40 activity. La presente invención se relaciona con compuestos que tienen la capacidad de modular la actividad de GPR40 y son por lo tanto útiles en el tratamiento de los trastornos relacionados con GPR40. Adicionalmente la invención se relaciona con compuestos, métodos para su preparación, composiciones farmacéuticas que contienen los compuestos y los usos de estos compuestos en el tratamiento de ciertos trastornos relacionados con la actividad de GPR40.