APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein. Se describen compuestos que inhiben la actividad de proteínas BcI-2 anti-apoptóticas, co...

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Main Authors GERARD SULLIVAN, GEORGE DOHERTY, AARON R. KUNZER, STEVEN ELMORE, ANDREW J. SOUERS, TODD M. HANSEN, LAURA HEXAMER, GARY T. WANG, LE WANG, ZHI-FU TAO, MICHAEL WENDT, HONG DING, XILU WANG, LISA HASVOLD, ROBERT MANTEI, XIAOHONG SONG, MILAN BRUNCKO
Format Patent
LanguageEnglish
Spanish
Published 26.02.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein. Se describen compuestos que inhiben la actividad de proteínas BcI-2 anti-apoptóticas, composiciones que contienen los compuestos y métodos para tratar enfermedades durante las cuales se expresa la proteína BcI-2 anti-apoptótica.
Bibliography:Application Number: MX20120013708