BIFUNCTIONAL POLYPEPTIDES

A bifunctional polypeptide comprising a specific binding partner for a peptide-MHC epitope, such as an antibody or a T cell receptor ("TCR"), and an immune effector, such as an antibody or a cytokine, the immune effector part being linked to the N- terminus of the peptide-MHC binding part....

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Bibliographic Details
Main Authors BENT KARSTEN JAKOBSEN, ANNELISE BRIGITTE VUIDEPOT, YI LI
Format Patent
LanguageEnglish
Spanish
Published 26.03.2012
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:A bifunctional polypeptide comprising a specific binding partner for a peptide-MHC epitope, such as an antibody or a T cell receptor ("TCR"), and an immune effector, such as an antibody or a cytokine, the immune effector part being linked to the N- terminus of the peptide-MHC binding part. Un polipéptido bifuncional que comprende un asociado de unión específico para un péptido-epítopo MHC, tal como un anticuerpo o un receptor de célula T ("TCR"), y un efector inmunitario, tal como un anticuerpo o una citocina, la parte efectora inmunitaria estando enlazada a N-terminal de la parte del péptido-MHC.
Bibliography:Application Number: MX20110012184