PYRIDAZINONE GLUCOKINASE ACTIVATORS

Provided herein are compounds of the formula (I), wherein X, Y, Q and R1 to R3 are defined in the specification, as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing...

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Main Authors JEFFERSON WRIGHT TILLEY, RAMAKANTH SARABU, NANCY-ELLEN HAYNES, YIMIN QIAN, LEE APOSTLE MCDERMOTT, STEVEN JOSEPH BERTHEL, ROBERT FRANCIS KESTER, NATHAN ROBERT SCOTT
Format Patent
LanguageEnglish
Spanish
Published 28.09.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are compounds of the formula (I), wherein X, Y, Q and R1 to R3 are defined in the specification, as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus. Se proporcionan aquí compuestos de fórmula (1) (ver fórmula (I)) en los que X, Y, Q y R1 a R3 se definen en la especificación, así como sales farmacéuticamente aceptables de los mismos, en los que los sustituyentes son como los que se describen en la especificación. Estos compuestos, y las composiciones farmacéuticas que los contienen, son útiles para el tratamiento de enfermedades metabólicas y trastornos como, por ejemplo, diabetes mellitus de tipo II.
Bibliography:Application Number: MX20100009922