ABNORMAL OUTPUT DETECTION SYSTEM FOR A BIOSENSOR

• Main Authors: WU, HUAN-PING, NELSON, CHRISTINE D, CARPENTER, SCOTT E
• Format: Patent
• Language: English; Spanish
• Published: 26.11.2008
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; DIAGNOSIS; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; IDENTIFICATION; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; SURGERY; TESTING; VINEGAR; WINE

A biosensor has an abnormal output detection system that determines whether an output signal from the redox reaction of an analyte has a normal or abnormal shape or configuration. The abnormal output detection system improves the accuracy and precision of the biosensor in determining whether an output signal has a shape or configuration that may not provide an accurate and/or precise analysis of a biological fluid. The biosensor generates an output signal in response to the redox reaction of the analyte. The biosensor normalizes the output signal and compares the normalized output signal with one or more control limits. The biosensor may generate an error signal when the normalized output signal is not within the control limits. The system finds particular application in gated amperometry for glucose determination using enzyme electrodes, where the normalized signal comprises the ratio of two current values in a given pulse. Un biosensor tiene un sistema de detección de salida anormal que determina si una señal de salida de la reacción redox de un analito ten una forma o configuración normal o anormal. El sistema de detección de salida anormal mejora la exactitud y precisión del biosensor para determinar si una señal de salida tiene una forma o configuración que no pudiera proporcionar un análisis exacto y/o preciso de un fluido biológico. El biosensor genera una señal de salida en respuesta a la reacción redox del analito. El biosensor normaliza la señal de salida y compara la señal normalizada de salida con uno o más límites de control. El biosensor podría generar una señal de error cuando la señal normalizada de salida no se encuentre dentro de los límites de control. La figura más representativa de la invención es la número 1.