NARCOTINE PURIFICATION PROCESS

A process for purifying Narcotine to remove color and impurities to form Noscapine. The process includes forming an aqueous isopropanol solution with the Narcotine product wherein the isopropanol concentration of the solution is about 20% to about 70% by volume; and adjusting the pH of the solution...

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Bibliographic Details
Main Authors KEITH G. TOMAZI, JOSEPH P. HAAR, JR, LEROY LOVE, JR
Format Patent
LanguageEnglish
Spanish
Published 15.10.2008
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Summary:A process for purifying Narcotine to remove color and impurities to form Noscapine. The process includes forming an aqueous isopropanol solution with the Narcotine product wherein the isopropanol concentration of the solution is about 20% to about 70% by volume; and adjusting the pH of the solution with a strong base to a pH of about 10 to about 14, wherein impurities are removed from the Narcotine product. Un proceso para purificar Narcotina, para retirar color e impurezas con el fin de formar Noscapina. El proceso incluye formar una solución acuosa de isopropanol con el producto de Narcotina, en donde la concentración de isopropanol de la solución es de aproximadamente 20% a aproximadamente 70% en volumen; y ajustar el pH de la solución con una base fuerte hasta un pH de entre aproximadamente 10 y aproximadamente 14, caracterizado porque se remueven las impurezas del producto Narcotina.
Bibliography:Application Number: MX20080012948