PYRAZOLES AS 11-BETA-HSD-1

Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for exa...

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Main Authors NANCY-ELLEN HAYNES, KEVIN RICHARD GUERTIN, SHERRIE LYNN PIETRANICO-COLE, QIANG ZHANG, MICHAEL PAUL MYERS, NADER FOTOUHI, KEVIN WILLIAM ANDERSON, PAMELA LOREEN ROSSMAN, JEFFERSON WRIGHT TILLEY, PAUL GILLESPIE, KSHITIJ CHHABILBHAI THAKKAR, LIDA QI, NATHAN ROBERT SCOTT, ROBERT ALAN GOODNOW, JR
Format Patent
LanguageEnglish
Spanish
Published 01.10.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome. Se proporcionan compuestos de la fórmula (I) así como sales farmacéuticamente aceptables de los mismos, en donde los sustituyentes tienen los significados definidos en la descripción. Estos compuestos y las composiciones farmacéuticas que los contienen son útiles para el tratamiento de enfermedades tales como la diabetes mellitus del tipo II y el síndrome metabólico. (ver fórmula).
Bibliography:Application Number: MX20080012017