PIPERAZINE-PIPERIDINE ANTAGONISTS AND AGONISTS OF THE 5-HT1A RECEPTOR

The present invention relates to novel piperazine-piperidine compounds. The compounds are useful as 5-HT1A binding agents, particularly as 5-HT1A receptor antagonists and agon f its. These compounds are useful in treating central nervous system disorders, such as cognition disorders, anxiety disorde...

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Main Authors JAMES JACOB BICKSLER, ANNMARIE LOUISE SABB, LISA MARIE HAVRAN, DAN CHAEKOO CHONG, GEORGE THEODORE GROSU, MAGDA ASSELIN, ZHONGUI SHEN, WAYNE EVERETT CHILDERS
Format Patent
LanguageEnglish
Spanish
Published 20.02.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to novel piperazine-piperidine compounds. The compounds are useful as 5-HT1A binding agents, particularly as 5-HT1A receptor antagonists and agon f its. These compounds are useful in treating central nervous system disorders, such as cognition disorders, anxiety disorders, depression and sexual dysfunction. La presente invencion se relaciona con compuestos de piperazina-piperidina novedosos. Los compuestos son utiles como agentes de enlace a 5-HT1A, particularmente como antagonistas y agonistas del receptor 5-HT1A. Estos compuestos son utiles para tratar desordenes del sistema nervioso central, tales como desordenes de cognicion, desordenes de ansiedad, depresion y disfuncion sexual.
Bibliography:Application Number: MX20070015678