INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING

The invention relates to the inhibition of vascular endothelial growth factor (VEGF) receptor signaling and hepatocyte growth factor (HGF) receptor signaling The invention provides compound A and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides c...

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Main Authors SAAVEDRA, OSCAR MARIO, ZHOU, NANCY Z, DEZIEL, ROBERT, ISAKOVIC LJUBOMIR, CLARIDGE, STEPHEN WILLIAM, ZHAN, LIJIE, RAEPPEL, FRANCK, RAEPPEL, STEPHANE, MANNION, MICHAEL, VAISBURG, ARKADII
Format Patent
LanguageEnglish
Spanish
Published 11.02.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to the inhibition of vascular endothelial growth factor (VEGF) receptor signaling and hepatocyte growth factor (HGF) receptor signaling The invention provides compound A and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions. Formula (A). La invencion se refiere a la inhibicion de la senalizacion del receptor de VEGF y la senalizacion del receptor de HGF; la invencion proporciona compuestos y metodos para inhibir la senalizacion del receptor de VEGF y la senalizacion del receptor de HGF; la invencion tambien proporciona composiciones y metodos para tratar enfermedades y condiciones proliferativas de las celulas.
Bibliography:Application Number: MX20070014617