A NOVEL PROCESS FOR THE PREPARATION OF (S)-(+)-N,N-DIMETHYL-3-(1- NAPHTHALENYLOXY)-3-(2-THIENYL)PROPANAMINE, A DULOXETINE INTERMEDIATE

Provided is a process for preparing a duloxetine intermediate,(S)-(+)-N,N-Dimethyl-3-(1- naphthalenyloxy)-3-(2-thienyl)propanamine (DNT), and its conversion to duloxetine or a pharmaceutically acceptable salt thereof. Se brinda un proceso para preparar un intermedio de duloxetina, (S)-(+)-N,N-Dimeti...

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Bibliographic Details
Main Authors YARON SHMUELY, MILI ABRAMOV, SANTIAGO INI
Format Patent
LanguageEnglish
Spanish
Published 11.01.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Provided is a process for preparing a duloxetine intermediate,(S)-(+)-N,N-Dimethyl-3-(1- naphthalenyloxy)-3-(2-thienyl)propanamine (DNT), and its conversion to duloxetine or a pharmaceutically acceptable salt thereof. Se brinda un proceso para preparar un intermedio de duloxetina, (S)-(+)-N,N-Dimetil-3-(1-naftaleniloxi)-3-(2-Tienil) propanamina (DNT), y la conversion en duloxetina o una sal de la misma aceptable para uso farmaceutico.
Bibliography:Application Number: MX20070014131