NOVEL SUBSTITUTED THIOPHENEPYRIMIDINONE DERIVATIVES AS INHIBITORS OF 17 ??-HYDROXYSTEROID DEHYDROGENASE

This invention relates to novel substituted thiophenepyrimidinone derivatives and their use in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent diseases or disorder, such as steroid hormone dependent diseases or disorders requiring inhibition of 17 a-hydr...

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Main Authors PASI KOSKIMIES, OLLI TANELI PENTIKAINEN, JOSEF MESSINGER, HEINRICH-HUBERT THOLE, PAULI SAARENKETO, BETTINA HUSEN, LEENA HIRVELA, PEKKA LEHTOVUORI, JOHANNA KIVINIEMI, MIKKO UNKILA, LILA PIRKKALA, BARTHOLOMEUS JOHANNES VAN STEEN
Format Patent
LanguageEnglish
Spanish
Published 26.06.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This invention relates to novel substituted thiophenepyrimidinone derivatives and their use in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent diseases or disorder, such as steroid hormone dependent diseases or disorders requiring inhibition of 17 a-hydroxysteroid dehydrogenase enzymes. Esta invencion se refiere a nuevos derivados de tiofenpirimidinona sustituida y a su uso en terapia, especialmente para su uso en el tratamiento y/o prevencion de una enfermedad o trastorno dependiente de hormonas esteroides, tal como enfermedades o trastornos dependientes de hormonas esteroides que requieren la inhibicion de encimas 17??-hidroxiesteroide deshidogenasas.
Bibliography:Application Number: MX20070007051