DIMETHOXY DOCETAXEL ACETONE SOLVATE ET METHOD FOR THE PREPARATION THEREOF
Pronalazak se odnosi na acetonske derivate dimetoksi docetaksela ili 4-acetoksi-2a-benzoiloksi-5p,20-epoksi-1 -hidroksi-7p,1 OP-dimetoksi-9-oksotaks-1 I -en-13 α -i I (2R.3S)-3-terc-butoksikarbonilamino-2-hidroksi-3-fenilpropionata i na njihovo dobijanje kristalizacijom iz hidro-acetonskog rastvora....
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| Main Authors | , |
|---|---|
| Format | Patent |
| Language | Bosnian English |
| Published |
10.06.2010
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Pronalazak se odnosi na acetonske derivate dimetoksi docetaksela ili 4-acetoksi-2a-benzoiloksi-5p,20-epoksi-1 -hidroksi-7p,1 OP-dimetoksi-9-oksotaks-1 I -en-13 α -i I (2R.3S)-3-terc-butoksikarbonilamino-2-hidroksi-3-fenilpropionata i na njihovo dobijanje kristalizacijom iz hidro-acetonskog rastvora.
The acetone solvate (A) of 4-acetoxy-2alpha -benzoyloxy-5beta ,20-epoxy-1-hydroxy-7beta ,10beta -dimethoxy-9-oxo-tax-11-en-13alpha -yl (2R,3S)-3-tert. butoxycarbonylamino-2-hydroxy-3-phenylpropionate (I) (i.e. dimethoxy docetaxel) (preferably containing 5-7 wt. % acetone) is new. An independent claim is included for the preparation of (A). ACTIVITY : Cytostatic. MECHANISM OF ACTION : None given in the source material. |
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| AbstractList | Pronalazak se odnosi na acetonske derivate dimetoksi docetaksela ili 4-acetoksi-2a-benzoiloksi-5p,20-epoksi-1 -hidroksi-7p,1 OP-dimetoksi-9-oksotaks-1 I -en-13 α -i I (2R.3S)-3-terc-butoksikarbonilamino-2-hidroksi-3-fenilpropionata i na njihovo dobijanje kristalizacijom iz hidro-acetonskog rastvora.
The acetone solvate (A) of 4-acetoxy-2alpha -benzoyloxy-5beta ,20-epoxy-1-hydroxy-7beta ,10beta -dimethoxy-9-oxo-tax-11-en-13alpha -yl (2R,3S)-3-tert. butoxycarbonylamino-2-hydroxy-3-phenylpropionate (I) (i.e. dimethoxy docetaxel) (preferably containing 5-7 wt. % acetone) is new. An independent claim is included for the preparation of (A). ACTIVITY : Cytostatic. MECHANISM OF ACTION : None given in the source material. |
| Author | PERRIN, MARC-ANTOINE DIDIER, ERIC |
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| DocumentTitleAlternate | ACETONSKI SOLVATI DIMETOKSI DOCETAKSELA I POSTUPCI ZA NJIHOVO DOBIJANJE |
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| Snippet | Pronalazak se odnosi na acetonske derivate dimetoksi docetaksela ili 4-acetoksi-2a-benzoiloksi-5p,20-epoksi-1 -hidroksi-7p,1 OP-dimetoksi-9-oksotaks-1 I -en-13... |
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| Title | DIMETHOXY DOCETAXEL ACETONE SOLVATE ET METHOD FOR THE PREPARATION THEREOF |
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