Un sel de sodium du n-((1,2,3,5,6,7-hexahydro-s-indacen-4 -yl)carbamoyl)-1-isopropyl-1h-pyrazole-3-sulfonamide

La présente invention concerne un sel de sodium de n-((1,2,3,5,6,7-hexahydro-s-indacèn- 4-yl)carbamoyl)-1-isopropyl-1h-pyrazole-3-sulfonamide et des hydrates, solvates et formes polymorphes de celui-ci. La présente invention concerne en outre des compositions pharmaceutiques comprenant ce composé, e...

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Bibliographic Details
Main Authors MILLER, David, DEL RIO GANCEDO, Susana, STRATFORD, Samuel Alexander, MACLEOD, Angus
Format Patent
LanguageFrench
Published 31.08.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:La présente invention concerne un sel de sodium de n-((1,2,3,5,6,7-hexahydro-s-indacèn- 4-yl)carbamoyl)-1-isopropyl-1h-pyrazole-3-sulfonamide et des hydrates, solvates et formes polymorphes de celui-ci. La présente invention concerne en outre des compositions pharmaceutiques comprenant ce composé, et l'utilisation de ce composé dans le traitement et la prévention de troubles médicaux et de maladies, plus particulièrement par inhibition de nlrp3. The present invention relates to a sodium salt ofN-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1H-pyrazole-3-sulfonamide and to hydrates, solvates and polymorphic forms thereof. The present invention further relates to pharmaceutical compositions comprising this compound and the use of this compound in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.
Bibliography:Application Number: MA20190048051