COMBINAISONS D'ARNM CODANT POUR DES POLYPEPTIDES DE MODULATION IMMUNITAIRE ET LEURS UTILISATIONS

The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of combinations of immunomodulatory polynucleotides (e.g., mRNAs) encoding an immune response primer polypeptide (e.g., an interleukin 23 (IL-23) polypeptide or an interleukin 36γ (IL-36-gamma) po...

Full description

Saved in:
Bibliographic Details
Main Authors PRESNYAK, Vladimir, KUMARASINGHE, Ellalahewage, Sathyajith, HOGE, Stephen, BENENATO, Kerry, MCFADYEN, lAIN, FREDERICK, Joshua, BAI, Ailin, HEWITT, Susannah
Format Patent
LanguageFrench
Published 27.03.2019
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of combinations of immunomodulatory polynucleotides (e.g., mRNAs) encoding an immune response primer polypeptide (e.g., an interleukin 23 (IL-23) polypeptide or an interleukin 36γ (IL-36-gamma) polypeptide), and an immune response co-stimulatory signal polypeptide (e.g., an OX40L polypeptide).
Bibliography:Application Number: MA20170045035