PROCEDE DE PREPARATION DE DERIVES D'OXALYL-AMINO-ACIDES

The invention relates to oxalylamino acid derivatives of the formula I in which R and R' are identical or different and are C1-C6 -alkyl or hydrogen, R1 is hydrogen or C1-C4-alkyl, R2 is hydrogen, C1-C6-alkyl, C1-C3-alkoxy, carboxyl, C1-C6-alkoxycarbonyl, aryl, SH, NH2 or halogen, where the alk...

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Bibliographic Details
Main Authors E. BAADER, H. BURGHARD, V.G. PUKALL
Format Patent
LanguageFrench
Published 31.12.1991
Edition5
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to oxalylamino acid derivatives of the formula I in which R and R' are identical or different and are C1-C6 -alkyl or hydrogen, R1 is hydrogen or C1-C4-alkyl, R2 is hydrogen, C1-C6-alkyl, C1-C3-alkoxy, carboxyl, C1-C6-alkoxycarbonyl, aryl, SH, NH2 or halogen, where the alkyl radicals are unsubstituted or substituted by aryl, OH, SH or NH2 or R1 and R2 together are a C2-C4-alkylene chain and the compounds in their predominantly pure D- and L-form and the physiologically tolerable salts. The compounds are distinguished as excellent inhibitors of prolyl hydroxylase and lysine hydroxylase.
Bibliography:Application Number: MA19910022422