FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME

The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment...

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Main Authors KULMAN, John, LIU, Tongyao, STEMMER, Willem, WANG, Chia-wei, VARFAJ, Fatbardha, CHANG, Pei-yun, TOBY, Garabet, JIANG, Haiyan, GEETHING, Nathan, WANG, Deping, DING, Sheng, SCHELLENBERGER, Volker, PETERS, Robert, SILVERMAN, Joshua, MEI, Baisong, SPINK, Benjamin
Format Patent
LanguageEnglish
Lithuanian
Published 10.01.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor Vlll-related diseases, disorders, and conditions.
AbstractList The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor Vlll-related diseases, disorders, and conditions.
Author SILVERMAN, Joshua
VARFAJ, Fatbardha
SCHELLENBERGER, Volker
GEETHING, Nathan
TOBY, Garabet
STEMMER, Willem
PETERS, Robert
CHANG, Pei-yun
JIANG, Haiyan
MEI, Baisong
WANG, Chia-wei
LIU, Tongyao
SPINK, Benjamin
DING, Sheng
KULMAN, John
WANG, Deping
Author_xml – fullname: KULMAN, John
– fullname: LIU, Tongyao
– fullname: STEMMER, Willem
– fullname: WANG, Chia-wei
– fullname: VARFAJ, Fatbardha
– fullname: CHANG, Pei-yun
– fullname: TOBY, Garabet
– fullname: JIANG, Haiyan
– fullname: GEETHING, Nathan
– fullname: WANG, Deping
– fullname: DING, Sheng
– fullname: SCHELLENBERGER, Volker
– fullname: PETERS, Robert
– fullname: SILVERMAN, Joshua
– fullname: MEI, Baisong
– fullname: SPINK, Benjamin
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Snippet The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
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