PYRAZOLE-AMIDE COMPOUND AND MEDICINAL USES THEREFOR

The present invention relates to a combination drug comprising (a) compound represented by the formula [I]:wherein n is 1 or 2, or a pharmaceutically acceptable salt thereof; and(b) at least one other medicament effective for the prophylaxis or treatment of a disease selected from the group consisti...

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Bibliographic Details
Main Authors MOTOMURA, Takahisa, SHOMI, Gakujun
Format Patent
LanguageEnglish
Lithuanian
Published 10.04.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a combination drug comprising (a) compound represented by the formula [I]:wherein n is 1 or 2, or a pharmaceutically acceptable salt thereof; and(b) at least one other medicament effective for the prophylaxis or treatment of a disease selected from the group consisting of diabetes such as (i) type 1 diabetes or (ii) type 2 diabetes, insulin resistance syndrome, metabolic syndrome, hyperglycemia, hyperlactacidemia, diabetic complications such as (i) diabetic neuropathy, (ii) diabetic retinopathy, (iii) diabetic nephropathy or (iii) cataract, cardiac failure such as (i)acute cardiac failure or (ii) chronic cardiac failure, cardiomyopathy, myocardial ischemia, myocardial infarction, angina pectoris, dyslipidemia, atherosclerosis, peripheral arterial disease, intermittent claudication, chronic obstructive pulmonary disease, brain ischemia, cerebral apoplexy, mitochondrial disease, mitochondrial encephalomyopathy, cancer, pulmonary hypertension and Alzheimer disease, wherein the medicament (b) is/are administered simultaneously, separately or continuously.
Bibliography:Application Number: LT14763385T