CEPHALOSPORIN DERIVATIVES

Cephalosporin compound(I), its avirulent salt, ester, hydrate, solvation, and its isomer are claimed. Thus, title compound(I) and its derivatives are prepared by reacting compound(II) with compound(III) in the presence of solvent followed by reduction of S-oxide S->(O)n. In formula, R1 is H, C1-4...

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Main Authors BANG, CHAN-SIK, KIM, SUNG-ILL, WOO, YOUNG-MIN, YEU, JAE-HONG, CHON, JAE-HOON, LIM, JONGAN, YANG, DUK-HO, OH, HUN-SEUNG, KIM, SAM-SIK, KIM, YONG-JOO, LEE, TAE-HEE, KIM, SE-HO
Format Patent
LanguageEnglish
Korean
Published 21.04.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Cephalosporin compound(I), its avirulent salt, ester, hydrate, solvation, and its isomer are claimed. Thus, title compound(I) and its derivatives are prepared by reacting compound(II) with compound(III) in the presence of solvent followed by reduction of S-oxide S->(O)n. In formula, R1 is H, C1-4 alkenyl, C3-4 alkynyl, or -C(Ra)(Rb)COOH(Ra,Rb = H or alkenyl), R2 is H or amino group, R3 is H, C1-4 alkyl, or amino group, R4 is H or C1-4 alkyl, Q is CH or N, R5 is H or amino protecting group, R6 is C1-4 alkyl, C3-4 alkenyl, C3-4 alkyl, or -C(Ra)(Rb)CO2(R3), R7 is H or carboxyl protecting group, X is leaving group, n is 0 or 1.
Bibliography:Application Number: KR19930018466