NOVEL POLYPEPTIDES AND DNA ENCODING THE SAID POLYPEPTIDES

요약없음 Novel polypeptides have a modified amino acid sequence of human interleukin 1 ( alpha -type and beta -type) polypeptides in which a certain amino acid residue(s) in said amino acid sequence is(are) exchanged for other amino acid residue(s) and a certain amino acid residue(s) at the N-terminus a...

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Main Authors KAWASHIMA, HITOSHI, FURUTA, RYUJI, YAMAGISHI, JUNICHI, FUKUI, TOSHIKAZU, KOTANI, HIROTADA, YAMAYOSHI, MICHIKO
Format Patent
LanguageEnglish
Korean
Published 20.12.1996
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
SUGARS
VINEGAR
WINE
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Summary:요약없음 Novel polypeptides have a modified amino acid sequence of human interleukin 1 ( alpha -type and beta -type) polypeptides in which a certain amino acid residue(s) in said amino acid sequence is(are) exchanged for other amino acid residue(s) and a certain amino acid residue(s) at the N-terminus and/or at the C-terminus are optionally deleted. The polypeptides have no capacity to induce production of prostaglandin E2 but maintain other biological activities of human interleukin 1 such as activation of lymphocyte. They are expected to be useful as medicaments.
Bibliography:Application Number: KR19890001221