1,1-BIS(HYDROXY-METHYL) CYCLOALKANE COMPOUND

This invention relates to the compound having antagonisn against blood platelet activating factor(PAF), preparing process, its usage, and describes 1,1-bis(hydroxymethyl) cycloalkane compound having the following formula(I) : In the above formula, n is 0 or an integer between 2 and 7; A is alkyl gro...

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Bibliographic Details
Main Authors KIM, SI-HWAN, WOO, SOON-HYUNG, BAN, SOO-HO, JUNG, SUNG-KI, KIM, BYUNG-UK
Format Patent
LanguageEnglish
Korean
Published 24.10.1996
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:This invention relates to the compound having antagonisn against blood platelet activating factor(PAF), preparing process, its usage, and describes 1,1-bis(hydroxymethyl) cycloalkane compound having the following formula(I) : In the above formula, n is 0 or an integer between 2 and 7; A is alkyl group with linear and side chains comprised of carbons between 6 and 24, or CONR1R2 wherein R1 is hydrogen or alkyl group having carbons between 1 and 6, and R2 is alkyl group having carbons between 6 and 24; B is T-U-V(X-)q wherein T is simple covalent bond, or selected from -CO-, -PO3 and -C(O)NRb( Rb; hydrogen or acyl or alkyl group having carbons between 1 and 4), and U is -(CH2)e-(e; 1-10), and V is selected from the formulae where R3, R4 and R5 each is alkyl group having carbons(1-6) or hetero-ring with nitrogen; R6 is hydrogen, halogen or alkyl group having carbons(1-6); R7 is alkyl group having carbons between 1 and 6.
Bibliography:Application Number: KR19930005778