PROCESS FOR PREPARING N-(2-METHOXYETHYL)-NOROXYMORPHONE
N-(2-Methoxyethyl)-noroxymorphoen of formula (I) and its acid addn. salts are prepd. by reacting noroxymorphone of formula (II) with a 2- methoxyethyl halide of formula X-(CH2)2-OCH3 where X is Cl, Br or I. (I) is useful as a non-addictive analgesic. It is a opioid-like agonist-antagonist with a non...
Saved in:
Main Authors | , , |
---|---|
Format | Patent |
Language | English Korean |
Published |
20.09.1990
|
Edition | 5 |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | N-(2-Methoxyethyl)-noroxymorphoen of formula (I) and its acid addn. salts are prepd. by reacting noroxymorphone of formula (II) with a 2- methoxyethyl halide of formula X-(CH2)2-OCH3 where X is Cl, Br or I. (I) is useful as a non-addictive analgesic. It is a opioid-like agonist-antagonist with a non-morphine like activity profile not found in known cpds. It is 36 times as active as morphine in the writhing test. |
---|---|
Bibliography: | Application Number: KR19830002440 |