5-AMINO-6,8-DIFLUOROQUINOLONES AS ANTIBACTERIAL AGENTS

A 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7 -[4-(methyl)-1- piperazinly -4-oxo-3-quinoline carboxylic acid of formula (I) or its pharmaceutically acceptable acid addn. salt is prepd. In (I), R is hydrogen, cation or C1-6 alkyl; R1 is amine, hydroxy or C1-3 alkoxy; X is CH, CBr, CCl, CF, CCF3...

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Bibliographic Details
Main Authors TREHAN, ASHOK K, SANCHEZ, JOSEPH P
Format Patent
LanguageEnglish
Korean
Published 31.01.1990
Edition5
Subjects
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Summary:A 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7 -[4-(methyl)-1- piperazinly -4-oxo-3-quinoline carboxylic acid of formula (I) or its pharmaceutically acceptable acid addn. salt is prepd. In (I), R is hydrogen, cation or C1-6 alkyl; R1 is amine, hydroxy or C1-3 alkoxy; X is CH, CBr, CCl, CF, CCF3 or N; R2 is H or C1-6 alkyl. (I) is useful as an antibacterial agent.
Bibliography:Application Number: KR19860010553