DRUG-CONTAINING FIBERS

Drug-contg. fiber for retention in the gastro-intestial (GI) tract have a length/dia. ratio of at least 8, a dia. of at least 0.1mm and a length of at least 2mm. The drug is present as a core or a soln. or suspension in the fibers. The polymer is (a) permeable to GI fluid and opt. contains a porosig...

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Bibliographic Details
Main Author CURATOLO, WILLIAM J
Format Patent
LanguageEnglish
Korean
Published 31.01.1990
Edition5
Subjects
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Summary:Drug-contg. fiber for retention in the gastro-intestial (GI) tract have a length/dia. ratio of at least 8, a dia. of at least 0.1mm and a length of at least 2mm. The drug is present as a core or a soln. or suspension in the fibers. The polymer is (a) permeable to GI fluid and opt. contains a porosigen, (b) bioerodable in GI fluid, (c) impermeable to the drug and GI fluid and contains a porosigen or (d) microporous. The fibers provide controlled drug release in the upper GI tract.
Bibliography:Application Number: KR19870007531