ACIDIC INDOLE COMPOUNDS AND PROCESS FOR PREPARING THEREOF

Title compds. (I)[R1Q=H, C1-12 alkyl, alkoxy, mercapto, C1-4 alkylthio, alkylsulfinyl, alkylsulfonyl, OH; R2=H, C1-12 alkyl, Ph, benzyl; R3=H, C1-12 alkyl, alkoxy, mercapto, C1-4 alkylthio, phenylthio, C1-4 alkylsulfinyl, etc.; R4=A or B , useful as an anti- allergic agent, are prepd. Thus, 20.7g of...

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Bibliographic Details
Main Authors UNANGST, PAUL C, STABLER, S RUSSELL, CONNER, DAVID T
Format Patent
LanguageEnglish
Korean
Published 13.03.1989
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Title compds. (I)[R1Q=H, C1-12 alkyl, alkoxy, mercapto, C1-4 alkylthio, alkylsulfinyl, alkylsulfonyl, OH; R2=H, C1-12 alkyl, Ph, benzyl; R3=H, C1-12 alkyl, alkoxy, mercapto, C1-4 alkylthio, phenylthio, C1-4 alkylsulfinyl, etc.; R4=A or B , useful as an anti- allergic agent, are prepd. Thus, 20.7g of intermediate of 1-hexyl-3- methoxy-1H-indole-2-carboxylate ethyl ester was saponicated to give its carboxylate (product 14.1g, yield=75%).
Bibliography:Application Number: KR19850009255