PROCESS FOR PREPARING N-ALKENYL-3-HYDROXYBENXO (B) THIOPHONE-2-CARBOXAMIDE DERIVATIVES

• Main Authors: GALLAGHER TIMOTHY F, TISHLER ALLAN N, GOLDENBERG MARVIN M, WITZEL BRUCE D, DURETTE PHILIPPE L, RUPPRECHT KATHLEEN M
• Format: Patent
• Language: English; Korean
• Published: 25.02.1987
• Edition: 4
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

Benzothiophene (I) [R=hydrogen, lower alkyl, aryl, lower cycloalkyl, halo lower alkyl, hetero aryl, benzyl, lower alkenyl, lower alkynyl; n=0,1,2; X1,X2,X3,X4=R ; R1,R2,R3 = R, halo; R4=R, -CR1=CR2R3 is prepd. for use as an inibitor of lipoxygenase and cyclooxygenase. Compds. (II) is reacted with al...