PROCESS FOR THE PREPARATION OF OXYACETIC ACID DERIVATIVES

I (R1 = H, halogen, OH, alkyl, alkoxy; X = halo; n = 1,2; R2 = H, Ph, alkoxycarbonyl, alkyl, hexadodesyl, cyclohexyl, α- 4- (4-chlorobenzeaminoethyl)-phenoxy -α-cyclohexylacetoxy-cyclohexy) was prepared from the reaction of II and III. Thus, II was treated with EtONa followed by the addition of α-ha...

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Bibliographic Details
Main Authors HAMAZAKI YASHUHIKO, ISHIYAMA NOBUO, SATO REIKE, SERI KENJI, YAMAMOTO TOSHIYUKI
Format Patent
LanguageEnglish
Korean
Published 22.10.1984
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Summary:I (R1 = H, halogen, OH, alkyl, alkoxy; X = halo; n = 1,2; R2 = H, Ph, alkoxycarbonyl, alkyl, hexadodesyl, cyclohexyl, α- 4- (4-chlorobenzeaminoethyl)-phenoxy -α-cyclohexylacetoxy-cyclohexy) was prepared from the reaction of II and III. Thus, II was treated with EtONa followed by the addition of α-halogeno-cyclohexylacetic ester to give oxyacetic acid derivatives. The solvents of this reaction can be used non-functional organic solvents, such as dimethylformamido and acetone in a reactive condition.
Bibliography:Application Number: KR19810002248