신규 퀴놀린 유도체

• Main Authors: KULKE DANIEL, SELBACH CLAUDIA, HEISLER IRING, HUBSCH WALTER, ZHUANG WEI, GRIEBENOW NILS, TAHTAOUI CHOUAIB, BOERNGEN KIRSTEN
• Format: Patent
• Language: Korean
• Published: 30.04.2024
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

본 발명은 화학식 (I)의 신규 퀴놀린 화합물을 포함한다. JPEGpct00097.jpg2352 (여기서, A, R1, R2, R3, R4, R5, R6 및 Q는 본원에 정의된 바와 같음) 상기 화합물의 제조 방법, 상기 화합물을 제조하는 데 유용한 중간체 화합물, 상기 화합물을 포함하는 제약 조성물 및 조합물, 및 단독 작용제로서 또는 다른 활성 성분과 조합하여 질환, 특히 연충 감염의 치료, 제어 및/또는 예방을 위한 제약 조성물을 제조하기 위한 상기 화합물의 용도를 포함한다. The present invention covers new quinoline compounds of general formula (I) :in which A, R1, R2, R3, R4, R5, R6, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.