1 Composition for preventing improving or treating renal fibrosis comprising one or more active ingredients

• Main Authors: PARK JUNG SUN, KIM CHANG SEONG, BAE EUN HUI, MA SEONG KWON, WENJUAN SUN, KIM SOO WAN
• Format: Patent
• Language: English; Korean
• Published: 08.12.2023
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

본 발명은 신장섬유화증 예방, 개선 또는 치료용 약학조성물에 대한 것으로, 보다 구체적으로는 β-elemene과　Z-guggulsterone이 각각 또는 서로 협력하여 신장　세뇨관과　신장간질　섬유아세포에서 신장섬유화를 억제하는 것을 확인하고 이들의 신규 용도를 활용하여 개발된 1개 이상의 유효성분을 포함하는 신장섬유화증 예방, 개선 또는 치료용 약학조성물 및 건강기능식품에 관한 것이다. The present invention relates to a pharmaceutical composition for preventing, improving, or treating renal fibrosis, and more specifically, to a pharmaceutical composition and a health functional food for preventing, improving, or treating renal fibrosis comprising one or more active ingredients, wherein it was confirmed that β-elemene and Z-guggulsterone individually or in cooperation with each other inhibit renal fibrosis in renal tubules and renal interstitial fibroblasts, and the present invention was developed using novel uses of β-elemene and Z-guggulsterone.