Axl ANTI-AXL ANTIBODIES AND THEIR IMMUNOCONJUGATES AND USES THEREOF

Axl 단백질에 결합하는 중쇄 가변 영역 및/또는 경쇄 가변 영역을 포함하는 항체가 제공된다. 이러한 항체를 포함하는 면역 접합체, 약학 조성물과 키트도 또한 제공된다. An antibody or antibody fragment having a heavy chain variable region and/or light chain variable region that specifically binds to Ax1 protein. Immunoconjugates, pharmaceutical compositions and kits compr...

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Bibliographic Details
Main Authors CHANG HWAI WEN, FREY GERHARD, SHORT JAY M
Format Patent
LanguageEnglish
Korean
Published 28.11.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Axl 단백질에 결합하는 중쇄 가변 영역 및/또는 경쇄 가변 영역을 포함하는 항체가 제공된다. 이러한 항체를 포함하는 면역 접합체, 약학 조성물과 키트도 또한 제공된다. An antibody or antibody fragment having a heavy chain variable region and/or light chain variable region that specifically binds to Ax1 protein. Immunoconjugates, pharmaceutical compositions and kits comprising the antibodies and antibody fragments are also provided. Also disclosed are methods of treating Ax1-expressing cancers using the antibodies, antibody fragments, immunoconjugates and pharmaceutical compositions of the present invention.
Bibliography:Application Number: KR20237040162