Composition for preventing alleviating and treating Renal fibrosis through mitochondrial function improvement

• Main Authors: PARK JUNG SUN, BAE EUN HUI, MA SEONG KWON, KIM SOO WAN, YANG EUN MI
• Format: Patent
• Language: English; Korean
• Published: 18.08.2023
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to a pharmaceutical composition for preventing, improving or treating renal fibrosis. More specifically, the present invention relates to a pharmaceutical composition and health functional food for preventing, alleviating or treating renal fibrosis which reveal the mechanism that inhibits renal fibrosis through reduction of mitochondrial oxidative stress and recovery of mitochondrial membrane potential damage, and contain substances that act on the mechanism as active ingredients. 본 발명은 신장섬유화증 예방, 개선 또는 치료용 약학조성물에 대한 것으로, 보다 구체적으로는 미토콘드리아 산화 스트레스　감소 및 미토콘드리아　막전위　손상　회복을 통해 신장섬유화를 억제하는 기전을 밝히고, 상기 기전에 작용하는 물질을 유효성분으로 포함하는 신장섬유화증 예방, 개선 또는 치료용 약학조성물 및 건강기능식품에 관한 것이다.