A PREPARING METHOD OF TORREYA NUCIFERA SEED EXTRACT

• Main Authors: AHN SOON CHEOL, YU SUN NYOUNG, PARK BO BAE, KIM SANG HUN, HWANG YOU LIM, KIM JI WON, KIM KWANG YOUN
• Format: Patent
• Language: English; Korean
• Published: 07.07.2023
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

One aspect relates to a method for manufacturing a Torreya nucifera seed extract. The Torreya nucifera seed extract manufactured according to an aspect inhibits inhibits alpha-glucosidase and protein dephosphorylation enzyme 1B, improves the binding ability of blood insulin and insulin receptor, and improves insulin resistance or insulin sensitivity by increasing insulin receptor expression, thereby being able to exhibit an effect of preventing or treating diabetes. In addition, the Torreya nucifera seed extract according to one aspect is a natural product and has low cytotoxicity, so it can contribute to the diabetes-related market/industry. 일 양상은 비자나무 종자 추출물의 제조 방법에 관한 것이다. 일 양상에 따라 제조된 비자나무 종자 추출물은 알파글루코시데이즈 및 단백질 탈인산화 효소 1B를 저해하며, 혈중 인슐린과 인슐린 수용체의 결합 능력을 증진시키고, 인슐린 수용체 발현을 증가시킴으로써 인슐린저항성을 개선 또는 인슐린민감성을 증가시킴으로써, 당뇨병의 예방 또는 치료 효과를 나타낼 수 있다. 또한, 일 양상에 따른 비자나무 종자 추출물은 천연물로서 세포 독성이 적으므로 당뇨병 관련 시장/산업에 이바지할 수 있다.