Nanoparticle complex for oral delivery of nafamostat and manufacturing method thereof

Provided in the present invention are an oral nafamostat delivery nanoparticle complex which allows oral delivery with increased half-life that alleviates the problem of existing nafamostat not being used as a treatment, and a manufacturing method thereof. The oral nafamostat delivery nanoparticle c...

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Bibliographic Details
Main Authors OH JUNG JU, KIM MIN JUN, LEE YONG KYU, CHOI YOUNG TAE, HWANG YONG HWA, LEE SEUNG AH
Format Patent
LanguageEnglish
Korean
Published 07.07.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided in the present invention are an oral nafamostat delivery nanoparticle complex which allows oral delivery with increased half-life that alleviates the problem of existing nafamostat not being used as a treatment, and a manufacturing method thereof. The oral nafamostat delivery nanoparticle complex can be used as a pharmaceutical composition for preventing or treating coronavirus infection. 기존의 나파모스타트가 치료제로서 사용되지 못한 문제점을 개선한, 반감기가 증가된 경구전달이 가능한 경구용 나파모스타트 전달 나노입자 복합체 및 제조방법을 제공한다. 상기 경구용 나파모스타트 전달 나노입자 복합체는 코로나바이러스 감염증 예방 또는 치료용 약학적 조성물로 이용될 수 있다.
Bibliography:Application Number: KR20210194191