SUBSTITUTED HETEROCYCLIC DERIVATIVE COMPOUNDS AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING THE SAME

• Main Authors: HAM SEOK WON, PARK MIN GI, JEONG MINSEON, LIM JI YOUN, CHOI JIA, HWANG HAYOUNG, KIM SANG BUM, KIM JINA, PARK CHEOL KYU, KIM SUHUI, MIN JU SIK, LEE SUNGWOO, JUNG KYUNG JIN, AN HONGCHAN, JEONG HYEON JU, PARK JONG MIN, KIM NAYEON, KIM SUNG JIN, HWANG JI SUN, KIM JUN KYUM, CHIN JUNGWOOK, KWON SUGYEONG, PARK JEONG EUN, KWON OH BIN, CHOI HYO JUNG, MIN KYUNGIM, CHO SUNG JIN, LEE SU JEONG, KIM EUN JUNG, KIM DONG HYUN
• Format: Patent
• Language: English; Korean
• Published: 29.06.2023
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides a substituted heterocyclic derivative compound of a novel structure that acts as a sterol regulatory element-binding protein-1 (SREBP1) inhibitor, a stereoisomer thereof, a hydrate thereof, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for preventing or treating cancer containing the same as an active ingredient. 본 발명은 SREBP1(sterol regulatory element-binding protein-1) 저해제로 작용하는 신규 구조의 치환된 헤테로고리 유도체 화합물, 이의 입체 이성질체, 이의 수화물 또는 이의 약학적으로 허용가능한 염 및 이를 유효성분으로 이를 포함하는 암의 예방 또는 치료용 약학적 조성물에 관한 것이다.