1- Novel salt of 1-sulfonyl pyrrole derivative preparation method thereof and pharmaceutical composition comprising thereof

• Main Authors: LEE JUNG WOO, YOON HONG CHUL, SHIN JAE EUI, PARK JOON TAE, LEE JAE HONG, HONG CHANG HEE, AN KYUNG MI, LEE SOO JIN, SEO HANNA
• Format: Patent
• Language: English; Korean
• Published: 22.06.2023
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a novel salt of a 1-sulfonyl pyrrole derivative, a novel salt with excellent in vivo solubility, stability, bioavailability, etc., a method for manufacturing the same, and a pharmaceutical composition containing the same. In order to solve the above problem, the present invention provides a novel salt of 1-(5-(2-fluorophenyl)-4-methoxy-1-((6-methoxypyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine, a method for manufacturing the same, and a pharmaceutical composition comprising the same as an active component. 본 발명은 1-설포닐 피롤 유도체의 신규 염에 관한 것으로, 생체 내 용해도, 안정성, 생체이용률 등이 우수한 신규 염, 이의 제조 방법 및 이를 포함하는 약학 조성물에 관한 것이다.