Composition for Improving Atopy Dermatitis Using an Extract of Rudbeckia laciniata

• Main Authors: LEE JAE YEON, HONG SEONG SU, AHN EUN KYUNG, CHO YOUNG RAK, JUNG YEON WOO
• Format: Patent
• Language: English; Korean
• Published: 13.06.2023
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

Disclosed in the present invention is a composition for alleviating atopic dermatitis using an extract of Rudbeckia laciniata that exhibits MDC and TARC expression inhibitory activity when treated with HaCaT cells, a human keratinocyte cell line treated with INF-γ and TNF-α. 본 발명은 INF-γ와 TNF-α로 처리된 인간각질형성세포주인 HaCaT 세포에 처리될 때 MDC 및 TARC 발현 억제 활성을 보이는 삼립국화 추출물을 이용한 아토피 피부염 개선용 조성물을 개시한다.