DNA Methods for quantification of cell-free DNA

The present invention relates to a quantification method for cell-free DNA (CFD), and more specifically, to a quantification method for fluorescence-based cell-free DNA (CFD), which established optimal storage conditions and freeze-thaw conditions for cell-free DNA in plasma from whole blood collect...

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Bibliographic Details
Main Author PARK KWON OH
Format Patent
LanguageEnglish
Korean
Published 10.04.2023
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Summary:The present invention relates to a quantification method for cell-free DNA (CFD), and more specifically, to a quantification method for fluorescence-based cell-free DNA (CFD), which established optimal storage conditions and freeze-thaw conditions for cell-free DNA in plasma from whole blood collection to plasma processing, and established standard linearity and accuracy. 본 발명은 무세포 DNA (세포 유리 DNA, cell-free DNA, CFD)의 정량화 방법에 관한 것으로, 보다 구체적으로 혈장(plasma) 내의 무세포 DNA에 대해 전혈 채혈 후 혈장 가공까지 최적의 보관 조건 및 동결-해동 조건을 구축하고, 표준 선형성과 정확성을 확립한 형광 기반의 무세포 DNA 정량화 방법에 관한 것이다.
Bibliography:Application Number: KR20210130500