세레블론 결합 화합물, 이의 조성물, 및 이에 의한 치료 방법

• Main Authors: ALEXANDER MATTHEW D, HARRIS III ROY L, HORN EVAN J, DALVIE DEEPAK, PLANTEVIN KRENITSKY VERONIQUE, MAYNE CHRISTOPHER, NORRIS STEPHEN, CORREA MATTHEW D, WHITEFIELD BRANDON W, HANSEN JOSHUA, SAPIENZA JOHN J, GRANT VIRGINIA HEATHER SHARRON, HUANG DEHUA, TEHRANI LIDA
• Format: Patent
• Language: Korean
• Published: 27.02.2023
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

하기 구조를 갖는 피페리딘 디온 화합물, 피페리딘 디온 화합물의 유효량을 포함하는 조성물, 및 안드로겐 수용체 매개 질병을 치료 또는 예방하기 위한 방법이 본 명세서에 제공된다: [화학식 I] JPEGpct00106.jpg2479 (상기 식에서, RN, R1, R2, R3, R4, RN, L, V, X, a, m, 및 n은 본 명세서에 정의된 바와 같음). Provided herein are piperidine dione compounds having the following structure:wherein RN, R1, R2, R3, R4, RN, L, V, X, a, m, and n are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.